Welcome to Hiromi Yanagisawa Laboratory at TARA!

Cells constantly receive cues from extracellular environment and respond by changing cytoskeletal organization and cellular functions as well as initiating transcriptional program, thereby maintaining homeostasis. The extracellular environment is comprised of extracellular matrix (ECM), ECM degrading enzymes and cleaved products, growth factors/cytokines, and physical factors such as hypoxia, hyperoxia, and mechanical forces. Our laboratory aims to elucidate the tissue-specific and disease-specific extracellular environment, focusing on ECM in the blood vessel wall, to understand the interactions between cells and the environment and how those interactions impact cellular functions and behavior. We apply the obtained knowledge to understand the normal developmental process and mechanism of diseases and to develop new therapeutic strategies. We take biochemical, molecular, and genetic engineering approaches to achieve these goals.

Based on my own experience as a trainee and PI in the U.S. research institution for more than 20 years, I run our laboratory to train the independent researcher with 4Cs (Challenging, Creative, Consistent, and Collegial). He/she will be the one who can find the most exciting question and come up with a strategy to find the answer.

Just come and see our laboratory. You are always welcome!


MEXT scholarship opportunity through University recommendation

January 21st, 2019|

The University of Tsukuba and MEXT (Ministry of Education, Culture, Sports, Science and Technology) offer a full-scholarship with stipend for selected international students who wish to obtain PhD. in Medical Science from the Program in Biomedical Sciences/Clinical Sciences (, Graduate School of Comprehensive Human Sciences beginning in October, 2020.

We are seeking highly motivated and talented medical or graduate students with a background in life sciences who have the ambition to become “trans-border” researchers and medical care specialists. Enrollment begins July, 2019 and the entrance examination will be held late August, 2019. The application detail will be available online July, 2019.

Please contact us using the contact form or mail to hky.tara@gmail.comif you are interested in conducting the doctorate work in our laboratory.

[Read more…]

  • TARAseminar

TARA Seminar on Feb. 5th

January 21st, 2019|

A TARA seminar will be held as follows.

Date: Tuesday, February 5th, 2019
Time: 18:00-19:00
Venue: Seminar room, 2F, Bldg. A, TARA Center [Map

Speaker: Haruka Ozaki, Ph.D.
(Associate professor, Department of Bioinformatics, Faculty of Medicine and Center For Artificial Intelligence Research University of Tsukuba)

Subject: “Bioinformatics for understanding complicated biological phenomena” [Read more…]

Member news

January 7th, 2019|


Satoko who covered administrative work since the very beginning of laboratory left at the end of last December.

She supported laboratory for four years. Some of  photos of the farewell party for Satoko have posted on the photo page.

We are recruiting undergraduates seeking for a senior thesis project and graduate students (including rotation students). Our lab is open for a lab visit.

Student Recruitment
Ph.D. program in Humanics

Ph.D. program in Humanics

Apply now for Apr. 2019 enrollment!