Welcome to Hiromi Yanagisawa Laboratory at TARA!

Cells constantly receive cues from extracellular environment and respond by changing cytoskeletal organization and cellular functions as well as initiating transcriptional program, thereby maintaining homeostasis. The extracellular environment is comprised of extracellular matrix (ECM), ECM degrading enzymes and cleaved products, growth factors/cytokines, and physical factors such as hypoxia, hyperoxia, and mechanical forces. Our laboratory aims to elucidate the tissue-specific and disease-specific extracellular environment, focusing on ECM in the blood vessel wall, to understand the interactions between cells and the environment and how those interactions impact cellular functions and behavior. We apply the obtained knowledge to understand the normal developmental process and mechanism of diseases and to develop new therapeutic strategies. We take biochemical, molecular, and genetic engineering approaches to achieve these goals.

Based on my own experience as a trainee and PI in the U.S. research institution for more than 20 years, I run our laboratory to train the independent researcher with 4Cs (Challenging, Creative, Consistent, and Collegial). He/she will be the one who can find the most exciting question and come up with a strategy to find the answer.

Just come and see our laboratory. You are always welcome!


New photos uploaded

November 1st, 2017

We had a Halloween party at the lab on 10/31. The photos from the party have been uploaded to the photo page.

Activity Log (Student)

October 19th, 2017

Thang participated in the 70th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery which was held in Sapporo, Hokkaido from 9/26 to 9/29. We have uploaded the photos from the meeting to the photo page.

His conference paper, which was presented last year in Vietnam, has published online. You can find it at the following web page. [Read more…]

News about our members

October 2nd, 2017

Kaori, a third year HBP student, left for Germany for her long-term research internship. She is staying at the Fraunhofer-Gesellschaft, Stuttgart for 6 months from September.

Caroline arrived in Tsukuba and she is going to stay in our laboratory as a participant of the MEXT-supported Inter-University Exchange Project.

The photos from the send-off party for Kaori and welcome lunch for Caroline have been added to the photo page.

>> News Archive

We are recruiting undergraduates seeking for a senior thesis project and graduate students (including rotation students). Our lab is open for a lab visit.
Student Recruitment