Welcome to Hiromi Yanagisawa Laboratory at TARA!

Cells constantly receive cues from extracellular environment and respond by changing cytoskeletal organization and cellular functions as well as initiating transcriptional program, thereby maintaining homeostasis. The extracellular environment is comprised of extracellular matrix (ECM), ECM degrading enzymes and cleaved products, growth factors/cytokines, and physical factors such as hypoxia, hyperoxia, and mechanical forces. Our laboratory aims to elucidate the tissue-specific and disease-specific extracellular environment, focusing on ECM in the blood vessel wall, to understand the interactions between cells and the environment and how those interactions impact cellular functions and behavior. We apply the obtained knowledge to understand the normal developmental process and mechanism of diseases and to develop new therapeutic strategies. We take biochemical, molecular, and genetic engineering approaches to achieve these goals.

Based on my own experience as a trainee and PI in the U.S. research institution for more than 20 years, I run our laboratory to train the independent researcher with 4Cs (Challenging, Creative, Consistent, and Collegial). He/she will be the one who can find the most exciting question and come up with a strategy to find the answer.

Just come and see our laboratory. You are always welcome!


New photos uploaded

September 18th, 2018|

Yoshito and Shin participated in the 16th Korea-Japan Joint Symposium on Vascular Biology, which was held in Osaka on Sep. 14th and 15th. Yoshito gave an invited presentation in the symposium. Shin gave a poster presentation, and won a poster award. We have added new photos from the symposium to the photo page.

New photos uploaded

September 13th, 2018|

Dr. Katja Schenke-Layland, the director of the Natural and Medical Sciences Institute at the University of Tübingen and a professor at Department of Women’s Health, Eberhard Karls University Tübingen, visited us with Dr. Eva Brauchle, a postdoc researcher at Dr. Schenke-Layland’s laboratory, and gave a talk in TARA seminar on Sep. 7th.

On the same day, a group of students from Ichikawa High School visited our center, and we introduced our research to them.

We have added some photos from the seminar and the lab tour to the photo page.

New photos uploaded

August 29th, 2018|

Dr. Peter Loskill from Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB at Stuttgart, Germany visited our lab with a graduate student, Oli, and gave a talk in TARA seminar on Aug. 27th. They came to Japan to participate in the 5th TERMIS World Congress in Kyoto.

The photos with them have been uploaded to the photo page.

We are recruiting undergraduates seeking for a senior thesis project and graduate students (including rotation students). Our lab is open for a lab visit.
Student Recruitment