Top 2018-07-12T16:49:47+00:00

Welcome to Hiromi Yanagisawa Laboratory at TARA!

Cells constantly receive cues from extracellular environment and respond by changing cytoskeletal organization and cellular functions as well as initiating transcriptional program, thereby maintaining homeostasis. The extracellular environment is comprised of extracellular matrix (ECM), ECM degrading enzymes and cleaved products, growth factors/cytokines, and physical factors such as hypoxia, hyperoxia, and mechanical forces. Our laboratory aims to elucidate the tissue-specific and disease-specific extracellular environment, focusing on ECM in the blood vessel wall, to understand the interactions between cells and the environment and how those interactions impact cellular functions and behavior. We apply the obtained knowledge to understand the normal developmental process and mechanism of diseases and to develop new therapeutic strategies. We take biochemical, molecular, and genetic engineering approaches to achieve these goals.

Based on my own experience as a trainee and PI in the U.S. research institution for more than 20 years, I run our laboratory to train the independent researcher with 4Cs (Challenging, Creative, Consistent, and Collegial). He/she will be the one who can find the most exciting question and come up with a strategy to find the answer.

Just come and see our laboratory. You are always welcome!


Activities and new photos

July 11th, 2018|Comments Off on Activities and new photos

Kaori attended RamanFest 2018 in Tokyo on Jun. 25th and 26th, and received the first prize for her poster presentation.

Hiromi, Yoshito and Kaori attended the 50th annual meeting of the Japanese Society for Matrix Biology and Medicine in Fukuoka on Jun. 29th and 30th. They participated in the workshop (Hiromi), oral presentation in “Tissue Remodeling” session (Yoshito), and poster session (Kaori). Congrats to Kaori for her YIA award! [Read more…]

Recent event at the lab

June 19th, 2018|Comments Off on Recent event at the lab

Dr. Arina Korneva, who just defended her thesis, came to visit our lab on June 12. She worked on vessel biomechanics in Prof. Jay Humphrey’s laboratory at Yale. [Read more…]

We are recruiting undergraduates seeking for a senior thesis project and graduate students (including rotation students). Our lab is open for a lab visit.
Student Recruitment