Welcome to Hiromi Yanagisawa Laboratory at TARA!

Cells constantly receive cues from extracellular environment and respond by changing cytoskeletal organization and cellular functions as well as initiating transcriptional program, thereby maintaining homeostasis. The extracellular environment is comprised of extracellular matrix (ECM), ECM degrading enzymes and cleaved products, growth factors/cytokines, and physical factors such as hypoxia, hyperoxia, and mechanical forces. Our laboratory aims to elucidate the tissue-specific and disease-specific extracellular environment, focusing on ECM in the blood vessel wall, to understand the interactions between cells and the environment and how those interactions impact cellular functions and behavior. We apply the obtained knowledge to understand the normal developmental process and mechanism of diseases and to develop new therapeutic strategies. We take biochemical, molecular, and genetic engineering approaches to achieve these goals.

Based on my own experience as a trainee and PI in the U.S. research institution for more than 20 years, I run our laboratory to train the independent researcher with 4Cs (Challenging, Creative, Consistent, and Collegial). He/she will be the one who can find the most exciting question and come up with a strategy to find the answer.

Just come and see our laboratory. You are always welcome!


TARA Seminar on Nov. 27

November 14th, 2018|

A TARA seminar will be held as follows.

Date: Tuesday, November 27th, 2018
Time: 13:00-14:00
Venue: Seminar room, 2F, Bldg. A, TARA Center [Map

Speaker: Tudorita Tumbar, Ph.D.
(Professor, Department of Molecular Biology and Genetics, Cornell University, USA)

Subject: “Molecular mechanisms of hair follicle stem cells function in normal homeostasis of adult skin” [Read more…]

Grant awarded

November 14th, 2018|

Yoshito has been awarded a research grant from MSD Life Science Foundation.

Aiko has been awarded research grants from Astellas Foundation for Research on Metabolic Disorders and from Takeda Science Foundation.

Career Opportunity

October 29th, 2018|

We are seeking a talented postdoctoral fellow to work on stem cell aging project. For more information, click HERE (external website).

★ Postdoc position available 


We are recruiting undergraduates seeking for a senior thesis project and graduate students (including rotation students). Our lab is open for a lab visit.

Student Recruitment