Welcome to Hiromi Yanagisawa Laboratory at TARA!

Cells constantly receive cues from extracellular environment and respond by changing cytoskeletal organization and cellular functions as well as initiating transcriptional program, thereby maintaining homeostasis. The extracellular environment is comprised of extracellular matrix (ECM), ECM degrading enzymes and cleaved products, growth factors/cytokines, and physical factors such as hypoxia, hyperoxia, and mechanical forces. Our laboratory aims to elucidate the tissue-specific and disease-specific extracellular environment, focusing on ECM in the blood vessel wall, to understand the interactions between cells and the environment and how those interactions impact cellular functions and behavior. We apply the obtained knowledge to understand the normal developmental process and mechanism of diseases and to develop new therapeutic strategies. We take biochemical, molecular, and genetic engineering approaches to achieve these goals.

Based on my own experience as a trainee and PI in the U.S. research institution for more than 20 years, I run our laboratory to train the independent researcher with 4Cs (Challenging, Creative, Consistent, and Collegial). He/she will be the one who can find the most exciting question and come up with a strategy to find the answer.

Just come and see our laboratory. You are always welcome!


Grant Awarded

February 15th, 2018

Aiko was awarded research grants from

Also, she was chosen as a Nanotech Research Professional (N.R.P.) by Nanotech Career-up Alliance.

Announcement of Yanagisawa Lab Seminar

February 10th, 2018

Our lab will host a seminar on Feb. 16 as follows.

When: 16:00-17:00 on Friday, Feb. 16, 2017
Venue: Seminar room, 2F, Bldg. A, TARA Center
Speaker: Hirano Tomoko, M.D.
               Department of Dermatology
               Kyoto University Graduate School of Medicine

“Elastic fiber network: three-dimensional visualization of the human skin by two-photon microscopy” [Read more…]

“Lab Members” & “Photos” Updated

February 9th, 2018

Jaakko completed his fellowship training in our laboratory.

Jaakko, thanks for all your critical comments during lab meeting and journal club and facilitating the discussion. We wish you the best for your next round of challenges!

Also, we have new members. Kae, Junior in Medical Sciences, joined our lab in last December, and Yen, the first year student in the Human Biology Program, in last January.
Welcome Kae and Yen! [Read more…]

>> News Archive

We are recruiting undergraduates seeking for a senior thesis project and graduate students (including rotation students). Our lab is open for a lab visit.
Student Recruitment